Well, done with it, in just under 40 hours...
Loved the story, all the characters were so well thought out and presented you just couldn't help but care for them (only Zaeed was a bit alienating with his over-the-top machismo) and the cliffhanger at the end will make the wait for the third episode really painful - I just hope I made the right choices... The quick time events were implemented very well, I'd never thought it would improve the dialogues but it really did... The ship gets really creepy after the one mission you're not Shepard (which I found could have been done better - it just interrupts the flow a bit too much when without warning you're in another character)... The mining game became tiring really fast (especially without upgrades), but after mining 3 systems completely clean I had more than enough resources to complete all upgrades (I was short only about 1000 Element Zero and Platinum)... I encountered only two bugs: Verner said I put a gun in his face when I didn't and although I did the mission with Grunt perfectly his special ability somehow wasn't unlocked...
Anyway, if the other games this year are on the same level (yes, I rate ME2 GotY-material), 2010 will be an awesome year for gaming...